The European program “Innovative Schools: Teaching & Learning in DIGITAL STEM LABS” aimed to upgrade secondary education by strengthening the digital and STEM skills of teachers and students. The main objective was to develop an innovative, digital, and interdisciplinary STEM teaching framework adapted to the requirements of distance and hybrid education. As part of the project, new educational material was designed and implemented, combining natural sciences, technology, engineering, and mathematics with modern pedagogical practices. Teachers from Turkey, Greece, Lithuania, and Spain actively participated in training, mobility, and good practice exchange programs, upgrading their digital and teaching skills. The program contributed significantly to strengthening the role and self-confidence of teachers in their local communities. At the same time, it supported the creation of high-quality digital education, suitable for modern teaching conditions, while strengthening networking between schools, universities, and experts in the field of educational technology. The program highlighted the need for the permanent integration of innovative STEM education into school curricula in order to bridge the gap between the knowledge and skills promoted by current education systems and the skills required by modern society and the labor market.